Biotilys / Maintains healthy skin balance

Description

Obtained by optimized fermentation, BIOTILYS® is a patented active ingredient based on the synergy of the lysate of the lactic probiotic Lactobacillus pentosus (known to act on intestinal immunity) (parabiotic fraction) and its postbiotic metabolites. BIOTILYS® enhances the skin’s natural defenses, by stimulating the expression of antimicrobial peptides (b-defensins, psoriasin, involved in innate immunity and protection against pathogenic bacteria) and by inhibiting the expression of the Toll-like receptor TLR-2 involved in the inflammatory response. As a skin tonic, BIOTILYS® acts to preserve healthy skin, protect the balance of the skin microbiota, improve skin hydration and strengthen the skin barrier function.

Cosmetic benefits

• Moisturizes the skin.
• Restores and strengthens the skin barrier
• Maintains the balance of the skin’s microbiome
• Makes the skin healthy
• Soothes the skin

INCI name: Aqua/Water, Propanediol, Lactobacillus ferment lysate

Recommended concentration: 2% (pH 4.0-10.0)
Solubility: partially soluble in water
Cosmos: approved

Skin microbiome

The skin is home to a large number of microorganisms, including bacteria and fungi that inhabit different areas of the skin. Bacteria are generally considered the most influential type of microorganisms, especially through the skin microbiome. Therefore, there are an average of 106 bacteria per cm2 of skin. This value varies because our skin contains multiple areas in which these microorganisms can develop. There are different types of places, moist, dry or oily, that allow microorganisms to develop and live within these complex ecosystems. Three genera of bacteria are particularly represented in the skin microbiome (Staphylococcus, Propionibacterium and Corynebacterium). In addition to these three genera, there is a great diversity of microorganisms present on our skin. This diversity is a key element in maintaining balance. It can vary depending on internal factors (genotype, age, gender) and external factors such as lifestyle, geographical location or frequent use of antibiotics or cosmetics. Each individual has their own specific skin microbiome that varies from one part of the body to another, its exposure, especially in protection against pathogens. However, if the microbiome is disrupted, this can lead to a reduction in the diversity of microorganisms, which can have dramatic consequences for the overall health of the skin. Skin disorders such as acne, atopic dermatitis, psoriasis are associated with an imbalance of the skin microbiome.

The World Health Organization (WHO) defines probiotics as “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host.” The gut microbiome is essential for maintaining good health, contributing to the digestion of food and the development and optimal functioning of the immune system. Interest in the beneficial functions of the gut microbiome has led researchers to focus on specific species from the genera Lactobacillus or Bifidobacterium.

The skin barrier can be disrupted by many factors, including sun, smoke, pollution, cold, excessive heat or allergens. These disturbances create an imbalance in the skin barrier and microbiome, which can lead to inflammation, loss of elasticity or proliferation of unwanted bacteria (i.e. proliferation of S.aureus in the case of atopic dermatitis, specific phylotypes of C. acnes in acne). Given their beneficial properties against damage to the intestinal epithelial barrier and skin damage, the use of probiotics in topical application seems to be an excellent component of care.

This is one of the reasons why BIOTILYS® was developed, an innovative active ingredient that harnesses all the benefits of probiotics. BIOTILYS® is produced from the lactic acid bacteria species Lactobacillus pentosus.